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Kathryn

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  1. Kathryn

    Triple-helix DNA?

    Kathryn replied to Xyph's topic in Biology

    Actually, 4 stranded DNA is VERY stable. It can only be formed by short sequences of guanine bases. Instead of assembling by Watson-Crick base pairing, it assembles via Hoosteen basepairing, so that a ring of 4 guanine bases comprises the base unit. This form of DNA can assemble in a varity of conformations, with both parallel and antiparallel strands, and is thought to play a role in sister chromatid alignment during recombination.
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