Cypher

Hi all, I am a product development engineer from a small medical device company that synthesizes a polyurethane based adhesive for surgical application. I am planning a tolerance study that will essentially set specifications for the tolerance of mass amounts in the formulation. However, with the number of raw materials involved a factorial DOE would not be an efficient design. I have researched the mixing DOE and some software out there that provides statistical analysis. The programs I've been investigating are Stat-Ease and DoE Fusion by S-matrix. I guess my question to the forum is has anyone had any experience with this type of study? And has anyone had any experience with the Stat-Ease and S-matrix software? Are there any other tools out there for MIX design? I appreciate any responses. Thanks. BP