zewel

im Egyptian chemist and microbiologist and i want to ask

who is the person that have license to open clinical laboratory and make the experiments in clinical lab

in egypt the law give license to chemists or biochemists if they take post graduated diploma of biochemistry after bsc to open clinical lab for chemistry only

aslo the law give license to microbiologists if they take post graduated diploma of microbiology after bsc to open clinical lab for microbiology only

aslo the law give license to physicians if they take master degree of clinical pathology after bachelor of medicine( although the physician dont know any thing about biochemistry or chemistry or microbiology before taking master of clinical pathology)

at the last Egyptian Ministry of Health want to prevent the chemists and microbiologists to open clinical lab in thier Specialties and to allow to physician only to open a clinical lab

and i want to ask about the situation in all countries in these topic

very good reply

i agree with u

while the the cyclization of ring is opened

The rules about who can do what vary from one country to another.

Here in the UK I could open a lab and do clinical analysis even though I am not (by any definition) a doctor. I am an analytical chemist but, strictly speaking I don't think that matters. Anyone could set up the lab if they could do the work (if they could not do the work not then it would be fraud).

I would have a very difficult time setting up a lab because people wouldn't want to trust a lab that has not got a reputation from years of work.

thanks my friend very much

I've answered these questions in my last two posts. What I think might help is if I use a hypothetical example.

 

The central dogma in biochemistry is that DNA produces mRNA, which in turn produces a protein. So the scheme is:

 

DNA [math]\leftrightarrow[/math] mRNA [math]\rightarrow[/math] Protein

 

You'll notice that arrow linking DNA to mRNA goes two ways. This is because there's transcription and reverse transcription (such as in viruses).

 

Let's invent a protein. We'll call it 'SFN'. This protein is a growth receptor on the plasma membrane. When a hormone hits it, the cell knows when to divide and grow. So if SFN was active all the time, the cell would divide exponentially. You'd get cancer.

 

This is the gene for SFN:

 

5'-ATGCGACCCTCCGGGACGGCC-3'

 

This is the protein it will produce:

 

N-MRPSGTA-C

 

Now imagine that this protein needed the R residue (arginine, I've underlined it) to bind a hormone and let the cell know when to grow and divide.

 

If the DNA is exposed to damage (from U.V., oxygen, carcinogens found in cigarettes, or whatever) then there could be a mutation. The "CGA" part of the DNA (this codes for the arginine in the protein) could become CCA. What will this do? It will change the protein. Instead of getting an arginine as the second amino acid, you'll now get a proline. The protein now has a different shape.

 

What does this mean? It means that now the protein doesn't have the right amino acid to bind the hormone. It's no longer controlled by the body and the endocrine system. The result is that it's active all the time. It will result in a cancerous cell.

 

This is a simplified analogy. The sequence is actually from a real protein, EGFR1, which is hugely present in a LOT of cancers. The cell can normally cope with mutation events like this through repair mechanisms. But as we age (and as we're exposed to more mutagenic chemicals) we lose the 'safety nets' that our cells have evolved. The damage we get is cumulative.

 

I hope this helps you to understand. And I'll repeat the sentiments from my first post: if you don't think that progress is happening fast enough, get involved in the field and help out.

it is very very fantastic topic

but i have question

i know that every receptor have a specific hormone or specific protein

to bind in it as lock and Kay theory and these means that

the wrong protein (that come from mutation in DNA)can not bind with the receptors or what

thanks for replying about question 2 so acording the following topic the pharmacist and physician are not doctor coz doctor orginily it is latinian word means a teatcher so it specialist for the person who have PHD and physicain and pharmacists arenot doctors or i dont understand it

and the topic is

"Doctor, as a title, comes from the Latin term (gen.: doctoris) which means teacher. The word is originally an agentive noun of the verb docēre ('to teach'). It has been used continuously as an honored academic title for over a millennium in Europe, where it dates back to the rise of the university. This use spread to the Americas, former European colonies, and is now prevalent in most of the world. Abbreviated "Dr" or "Dr.", is used as a designation for a person who has obtained a doctorate (that is, a doctoral degree). Doctorates may be "research doctorates," or "professional doctorates". When addressing several persons of whom each holds a doctoral title, one can use the plural abbreviations "Drs." or in some languages,[which?] Dres., may be used, e.g., instead of Dr. Miller and Dr. Rubinstein: Drs. Miller and Rubinstein. When referring to relatives with the same surname, it is common to use the form "The Doctors Smith"

this is in link

http://en.wikipedia.org/wiki/Doctor_%28title%29

.......................................

the first question

who is the person that can open a clinical laboratory??

the physicain or clinical chemist or pharmacist or what

coz in egypt the government need to prevent the clinical chemist to open clinical laboratory and make the physician who only can open the labs

so i ask to know who is the person who have liscience to open clinical lab

in other countries

i think the lysozyme is denaturated because it is enzyme and enzyme is proteins

and the proteins in high temp is coagulated and denaturated

hi every one

im clinical chemist from egypt

i want to request about some questions

1-clinical chemist or physician who can open clinical laboratory?

2-the pharmacist and phyisician iare doctor or not

i konow that doctor is latin word means teatcher that have phD to teach on university but there is confusion between them

so the physician and pharmacist arenot doctors but it is supposed that the person who have PhD only called doctor

i want to know ur comments about these requests