I’m exploring a technical concept involving a sealed gel system that acts as a thermal transfer medium in a flexible, enclosed structure. The gel would be required to facilitate both heat and cold transfer by interacting with nearby chemical heat/cold sources (e.g., sodium acetate or urea-based reactions). It will be completely enclosed and not in contact with skin, but it needs to operate reliably across a temperature range of approximately 10°C to 45°C over repeated cycles. I’d be very grateful for your insight on the following: Material Compatibility – Would a gel composed of water, propylene glycol, glycerin, and a gelling agent like sodium polyacrylate or fumed silica maintain stable consistency and thermal responsiveness when subjected to heating and cooling over many cycles? Thermal Conductivity Considerations – Are there any additives you recommend to enhance heat and cold conduction, especially at the lower end of the temperature range, without compromising the gel’s integrity? Long-Term Durability – In a sealed but flexible environment, would such a gel formulation be prone to issues like phase separation, syneresis, microbial growth, or crystallisation under routine thermal cycling? Any guidance or references you can offer would be deeply appreciated.