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Ciak

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    Pharmacy Student

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  1. this is the fluoxetine synthesis and the von Braun reaction at the last step. I wanted to know if I can use this method to other synthesis too
  2. If I have 3o amine on a side chain, and I want to make it 2o amine by getting rid of -CH3, can I use BrCN and KOH ? Is this correct?
  3. Can i add NaCN to ClCH2CH2CH2Cl and only one Cl be replaced with CN? Is this based on the moles of NaCN I add?
  4. How do i end up with ClCOCH2CH2CH2Cl starting from ethene CH2CH2?
  5. No I need these in order to synthesize some drugs of the subject ''Organic Pharmaceutical Chemistry''
  6. Can someone help me synthesize BrCH2CH2Cl from CH2CH2? Is this way correct? CH2CH2 + HOCl—> OHCH2CH2Cl + PBr3–> BrCH2CH2Cl
  7. Hey everyone.. I need you help asap. I have 11 molecules I need to synthesize, starting from the basics like benzene and ethene,each time. The major problem with the amines is that I when I want to produce 1o or 2o amines I dont want a mixure of 1o,2o and 3o amines so I cant use the reaction: RCH2Cl+NH3 (but I can use RCOCl+ NH3 and then LiALH4). All the molecules are in the attached word document. Every little help or tip is valuable for me since my exams are pretty close. Thanks in advance Organic chemistry mol.docx
  8. And one more question... from aniline to phenol do I use NaNO2/HCl and then H2O? Is that right? *You are a life saver.. I have exams and as you can see synthesis are not my thing
  9. Hi everyone.. I need help to produce CH3O-benzene-CH2COCl (para thesis) starting from benzene. I tried to start with CH2COCl so i will have para thesis but when I react the molecule ( OH-benzene-CH2COCl) with NaOH/CH3Br in order to have the ether, CH2COCl will react with NaOH too... Is there any other way to do this?
  10. At the stage when Ch3NH2 react with ClCH2COOCH3 i think we will have a mixure of 1o,2o,3o amines and we wont be able to get the one product i want.. is there any other way including the reaction of RCOCL+ RNH2?
  11. Hey everyone... I am desperate! Can someone help me with the synthesis of COOHCH2NHCH3 from CH2CH2?
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