Descartes have six characters: +x -x +y -y +z -z
Combine with factorial:
{+x-x+y-z+z-z} = 6! = 720
720 = 10 x 72
splitting group {+x-x+y-y+z-z} = 4 + 6:
Limited space of universe: 72 x 4 = 288, 288! = 7,196 x 10^584
+x+y+z-x-y-z = 72
+x+y-z-x-y+z = 72
+x+z-y-x-z+y = 72
+y+z-x-y-z+x = 72
Limited time of space: 72 x 6 = 432, 432! = 4,272 x 10^952.
+x-x+z+y-y-z = 72
+x-x-z+y-y+z = 72
+x-x+y+z-z-y = 72
+x-x-y+z-z+y = 72
+y-y-x+z-z+x = 72
+y-y+x+z-z-x = 72