FENIX drink

I will take that in mind in the future thanks, just wanted to sketch the background story of my question. Regarding the evidence, we have added the right ingredients at the right concentration to obtain the following 7 official EFSA claims, I have attached the links to the official European Commission reports: Choline contributes to the maintenance of normal liver function. https://efsa.onlinelibrary.wiley.com/doi/abs/10.2903/j.efsa.2011.2056 https://efsa.onlinelibrary.wiley.com/doi/abs/10.2903/j.efsa.2011.2203 Magnesium contributes to: 1. to reduction of tiredness and fatigue https:/efsa.onlinelibrary.wiley.com/doi/abs/10.2903/j.efsa.2010.1807 2. the normal functioning of the nervous system https://efsa.onlinelibrary.wiley.com/doi/abs/10.2903/j.efsa.2009.1216 3. electrolyte balance https://efsa.onlinelibrary.wiley.com/doi/abs/10.2903/j.efsa.2009.1216 Sodium & glucose enhance water absorption. https://efsa.onlinelibrary.wiley.com/doi/abs/10.2903/j.efsa.2011.2211 Potassium contributes to the normal functioning of the nervous system https://efsa.onlinelibrary.wiley.com/doi/abs/10.2903/j.efsa.2010.1469 Vitamin C contributes to: 1. the normal function of the immune system http://www.efsa.europa.eu/en/efsajournal/doc/1226.pdf 2. the protection of cells from oxidative stress https://efsa.onlinelibrary.wiley.com/doi/abs/10.2903/j.efsa.2009.1226 3. reduction of tiredness and fatigue https://efsa.onlinelibrary.wiley.com/doi/abs/10.2903/j.efsa.2010.1815 4. the normal functioning of the nervous system https://efsa.onlinelibrary.wiley.com/doi/abs/10.2903/j.efsa.2009.1226 Vitamin E contributes to the protection of cells from oxidative stress. https://efsa.onlinelibrary.wiley.com/doi/abs/10.2903/j.efsa.2010.1816 Regarding the vit B's, there are also 2 claims to make: 1. vit B1, B3 and B6 contribute to the normal functioning of the nervous system 2. vit B3 contributes to reduction of tiredness and fatigue. These official health claims are part of the aim to support our body during the process. Regarding lowering hangover symptoms and specific liver support we have selected 4 plant derived ingredients from which I have added the conclusion of the articles (with title so everyone can look them up) below: Silymarin SILYMARIN RETARDS THE PROGRESSION OF ALCOHOL-INDUCED HEPATIC FIBROSIS IN BABOONS Conclusions Silymarin retards the development of alcohol-induced hepatic fibrosis in baboons, consistent with several positive clinical trials. SILYMARIN PROTECTS AGAINST ACUTE ETHANOL‐INDUCED HEPATOTOXICITY IN MICE Conclusions Silymarin protects against the liver injury caused by acute EtOH administration. In view of its nontoxic nature, it may be developed as an effective therapeutic agent for alcohol‐induced liver disease by its antioxidative stress and anti‐inflammatory features. PROTECTIVE EFFECTS OF SILYMARIN, A MILK THISTLE (SILYBIUM MARIANUM) DERIVATIVE ON ETHANOL-INDUCED OXIDATIVE STRESS IN LIVER. Conclusion Silybin showed a significant hepatoprotective activity, but activity was less than that of ascorbic acid. Furthermore, preventive measures were more effective than curative treatment. Zingiber Officinale PROTECTIVE EFFECT OF GINGER AGAINST ALCOHOL-INDUCED RENAL DAMAGE AND ANTIOXIDANT ENZYMES IN MALE ALBINO RATS. Conclusion The antioxidant compounds of ginger may modulate the oxidative stress induced by alcohol. SOD, ascorbic acid, and GSH levels were decreased, and GST activity was increased in alcohol treated rats. However, after treatment with the extract of ginger, these parameters came to normal. CLINICAL EFFECTIVENESS OF KSS FORMULA, A TRADITIONAL FOLK REMEDY FOR ALCOHOL HANGOVER SYMPTOMS. Conclusion These findings suggest the possibility that KSS formula may become a candidate for alcohol hangover remedy when administered prophylactically. EFFECT OF A GINGER EXTRACT ON PREGNANCY‐INDUCED NAUSEA: A RANDOMISED CONTROLLED TRIAL. Conclusion Ginger can be considered as a useful treatment option for women suffering from morning sickness and therefore it could be used as a candidate for the prevention and treatment of hangover. EFFECTS OF GINGER ON MOTION SICKNESS AND GASTRIC SLOW-WAVE DYSRHYTHMIAS INDUCED BY CIRCULAR VECTION. Conclusion Ginger effectively reduces nausea, tachygastric activity, and vasopressin release induced by circular vection. In this manner, ginger may act as a novel agent in the prevention and treatment of motion sickness. PYRUS PYRIFOLIA (KOREAN PEAR) JUICE EFFECT OF KOREAN PEAR (PYRUSPYRIFOLIA CV. SHINGO) JUICE ON HANGOVER SEVERITY FOLLOWING ALCOHOL CONSUMPTION Conclusion The results have showed that Korean pear stimulated the activities of both ADH and ALDH and decreased the blood alcohol level in ALDH2 genotype. Therefore, Korean pear juice could alleviate hangover, and its detoxification of alcohol seemed to be related to the genetic variation of ALDH2. The results suggested that human ALDH2 polymorphisms could lead to individual variations on alcohol detoxification. Hence, Pyrus pyrifolia might be a useful and effective food supplement in alleviation of hangover and detoxification of alcohol through stimulating the activities of both ADH and ALDH. OPUNTIA FICUS-INDICA EFFECT OF OPUNTIA FICUS INDICA ON SYMPTOMS OF THE ALCOHOL HANGOVER. Conclusions The symptoms of the alcohol hangover are largely due to the activation of inflammation. An extract of the OFI plant has a moderate effect on reducing hangover symptoms, apparently by inhibiting the production of inflammatory mediators. EVALUATION OF OPUNTIA FICUS INDICA F. INERMIS FRUIT JUICE HEPATOPROTECTIVE EFFECT UPON ALCOHOL TOXICITY IN RATS Conclusion Therefore, Opuntia ficus-indica might be effective in treating hangover and protecting liver from alcohol toxicity due to its anti-inflammatory and strong antioxidant properties. If anyone has more questions, or remarks, please let me know. d Alcohol hangover is not yet fully understood but the existing evidence indeed point out that it's a combination of dehydration (that's why we add electrolytes and glucose), increased concentration of acetaldehyde (which we lower by using the Nashi pear juice and also inflammation (we added several anti-inflammatory agents). Scientists didn't yet discover the ultimate antidote but at least we can lower already the hangover symptoms significantly. Regarding the evidence, we have added the right ingredients at the right concentration to obtain the following 7 official EFSA claims, I have attached the links to the official European Commission reports: Choline contributes to the maintenance of normal liver function. https://efsa.onlinelibrary.wiley.com/doi/abs/10.2903/j.efsa.2011.2056 https://efsa.onlinelibrary.wiley.com/doi/abs/10.2903/j.efsa.2011.2203 Magnesium contributes to: 1. to reduction of tiredness and fatigue https:/efsa.onlinelibrary.wiley.com/doi/abs/10.2903/j.efsa.2010.1807 2. the normal functioning of the nervous system https://efsa.onlinelibrary.wiley.com/doi/abs/10.2903/j.efsa.2009.1216 3. electrolyte balance https://efsa.onlinelibrary.wiley.com/doi/abs/10.2903/j.efsa.2009.1216 Sodium & glucose enhance water absorption. https://efsa.onlinelibrary.wiley.com/doi/abs/10.2903/j.efsa.2011.2211 Potassium contributes to the normal functioning of the nervous system https://efsa.onlinelibrary.wiley.com/doi/abs/10.2903/j.efsa.2010.1469 Vitamin C contributes to: 1. the normal function of the immune system http://www.efsa.europa.eu/en/efsajournal/doc/1226.pdf 2. the protection of cells from oxidative stress https://efsa.onlinelibrary.wiley.com/doi/abs/10.2903/j.efsa.2009.1226 3. reduction of tiredness and fatigue https://efsa.onlinelibrary.wiley.com/doi/abs/10.2903/j.efsa.2010.1815 4. the normal functioning of the nervous system https://efsa.onlinelibrary.wiley.com/doi/abs/10.2903/j.efsa.2009.1226 Vitamin E contributes to the protection of cells from oxidative stress. https://efsa.onlinelibrary.wiley.com/doi/abs/10.2903/j.efsa.2010.1816 Regarding the vit B's, there are also 2 claims to make: 1. vit B1, B3 and B6 contribute to the normal functioning of the nervous system 2. vit B3 contributes to reduction of tiredness and fatigue. These official health claims are part of the aim to support our body during the process. Regarding lowering hangover symptoms and specific liver support we have selected 4 plant derived ingredients from which I have added the conclusion of the articles (with title so everyone can look them up) below: Silymarin SILYMARIN RETARDS THE PROGRESSION OF ALCOHOL-INDUCED HEPATIC FIBROSIS IN BABOONS Conclusions Silymarin retards the development of alcohol-induced hepatic fibrosis in baboons, consistent with several positive clinical trials. SILYMARIN PROTECTS AGAINST ACUTE ETHANOL‐INDUCED HEPATOTOXICITY IN MICE Conclusions Silymarin protects against the liver injury caused by acute EtOH administration. In view of its nontoxic nature, it may be developed as an effective therapeutic agent for alcohol‐induced liver disease by its antioxidative stress and anti‐inflammatory features. PROTECTIVE EFFECTS OF SILYMARIN, A MILK THISTLE (SILYBIUM MARIANUM) DERIVATIVE ON ETHANOL-INDUCED OXIDATIVE STRESS IN LIVER. Conclusion Silybin showed a significant hepatoprotective activity, but activity was less than that of ascorbic acid. Furthermore, preventive measures were more effective than curative treatment. Zingiber Officinale PROTECTIVE EFFECT OF GINGER AGAINST ALCOHOL-INDUCED RENAL DAMAGE AND ANTIOXIDANT ENZYMES IN MALE ALBINO RATS. Conclusion The antioxidant compounds of ginger may modulate the oxidative stress induced by alcohol. SOD, ascorbic acid, and GSH levels were decreased, and GST activity was increased in alcohol treated rats. However, after treatment with the extract of ginger, these parameters came to normal. CLINICAL EFFECTIVENESS OF KSS FORMULA, A TRADITIONAL FOLK REMEDY FOR ALCOHOL HANGOVER SYMPTOMS. Conclusion These findings suggest the possibility that KSS formula may become a candidate for alcohol hangover remedy when administered prophylactically. EFFECT OF A GINGER EXTRACT ON PREGNANCY‐INDUCED NAUSEA: A RANDOMISED CONTROLLED TRIAL. Conclusion Ginger can be considered as a useful treatment option for women suffering from morning sickness and therefore it could be used as a candidate for the prevention and treatment of hangover. EFFECTS OF GINGER ON MOTION SICKNESS AND GASTRIC SLOW-WAVE DYSRHYTHMIAS INDUCED BY CIRCULAR VECTION. Conclusion Ginger effectively reduces nausea, tachygastric activity, and vasopressin release induced by circular vection. In this manner, ginger may act as a novel agent in the prevention and treatment of motion sickness. PYRUS PYRIFOLIA (KOREAN PEAR) JUICE EFFECT OF KOREAN PEAR (PYRUSPYRIFOLIA CV. SHINGO) JUICE ON HANGOVER SEVERITY FOLLOWING ALCOHOL CONSUMPTION Conclusion The results have showed that Korean pear stimulated the activities of both ADH and ALDH and decreased the blood alcohol level in ALDH2 genotype. Therefore, Korean pear juice could alleviate hangover, and its detoxification of alcohol seemed to be related to the genetic variation of ALDH2. The results suggested that human ALDH2 polymorphisms could lead to individual variations on alcohol detoxification. Hence, Pyrus pyrifolia might be a useful and effective food supplement in alleviation of hangover and detoxification of alcohol through stimulating the activities of both ADH and ALDH. OPUNTIA FICUS-INDICA EFFECT OF OPUNTIA FICUS INDICA ON SYMPTOMS OF THE ALCOHOL HANGOVER. Conclusions The symptoms of the alcohol hangover are largely due to the activation of inflammation. An extract of the OFI plant has a moderate effect on reducing hangover symptoms, apparently by inhibiting the production of inflammatory mediators. EVALUATION OF OPUNTIA FICUS INDICA F. INERMIS FRUIT JUICE HEPATOPROTECTIVE EFFECT UPON ALCOHOL TOXICITY IN RATS Conclusion Therefore, Opuntia ficus-indica might be effective in treating hangover and protecting liver from alcohol toxicity due to its anti-inflammatory and strong antioxidant properties.

In fact I don't want to advertise at all, just want some feedback regarding the composition. No drip just a can in this case.

haha sorry maybe I didn't make that entirely clear. It is a water based drink so next to all the active ingredients there is indeed plenty of water. By the way, you should drink 2 cans (250 ml each) during the night out to use its full potential

Hello everyone, I would like utilise this community to get some feedback regarding my composed formula to diminish hangover symptoms and support our body during the degradation process of ethanol in a healthy way. My startup FENIX Hangover Care is currently performing a seed investment round to gather enough cash to start our first production in our Benelux (Belgium, Luxembourg & Netherlands) region. Doing so I'm of course also interested what this science community thinks about this idea/product, so all feedback is highly appreciated! We picked the ingredients for 2 main reasons: 1) Support the body while getting rid of the harmful by-products of alcohol (ROS (reactive oxygen species), acetaldehyde, inflammation, dehydration) 2) Lowering overall hangover symptoms as much as possible by selecting the most studied ingredients and adding them at the right concentration. We added the following ingredients: Choline: the only ingredients with EFSA (European Food Safety Authority) health claim regarding 'liver support' Silymarin (from Milk thistle): a strong antioxidant and anti-inflammatory Ginger Officinale: interesting data regarding morning sickness Opuntia Ficus Indica: anti-inflammatory and significant reduction of 3 hangover symptoms; nausea, dry mouth and appetite Nashi pear juice: interesting research from 2013 demonstrating its potential of increasing ALDH (aldehyde dehydrogenase; responsible for breakdown of acetaldehyde) and subsequently lowering overall hangover symptoms. minerals (Mg, K, Na): for rehydration and replenish lost electrolytes during alcohol consumption vitamines (vit C, vit E, vit B1, vit B3, vit B6): strong antioxidants and support of immune system + mental support N-acetylcysteine: precursor of glutathione, one of our strongest natural antioxidants If you would like to receive the links to the related articles, please let me know and we will provide (email removed)