kikothedog

Hi BabcockHall I am studying the bonding dynamics in several protein structures but my experiment is modifying several of the side chains causing additional conformational changes to my proteins. There are already several chemical groups that have been used successfully to protect residues during process which are later removed from the sample. The PI on my work suggested the introduction of a tetralinyl group but I have never used this before and he provided no more information as to how to go about this. If you have any suggestions they would be most welcome. I have passed the info back to the protein guys but they can be touchy about their work ruined for my enjoyment. Kiko

Thanks for the reply, guess I'll just pass the issue on to the protein chemists to figure out.

I'm an immunologist working on therapeutic proteins. I seem to do okay around all that chemical stuff we have in the lab without so far killing anyone, but really, thank you for the very unhelpful advise there!

Hi guys, is there anyone here that can tell my how to introduce a tetralinyl group into my sample. I have very little chemistry understanding so I have no idea which chemical solution to make up for this. Thanks for any and all help. Kiko