ozscience Posted October 23, 2016 Share Posted October 23, 2016 Hello all! I am studying for a Biochem exam and am having issues understanding how Koshland's Sequential model accounts for negative homotropic effectors. (aka, substrate binds and next substrate is less likely to bind leading to a higher cooperativity) If someone could please give me some sort of a link to a diagram or simply explain it to me that would be great! Google search is not working to well. Link to comment Share on other sites More sharing options...
BabcockHall Posted October 24, 2016 Share Posted October 24, 2016 You might try searching on negative cooperatively. In the book Structure and mechanism in protein science, Alan Fersht has a very brief treatment on pages 296-297 (second edition). Link to comment Share on other sites More sharing options...
Recommended Posts
Create an account or sign in to comment
You need to be a member in order to leave a comment
Create an account
Sign up for a new account in our community. It's easy!
Register a new accountSign in
Already have an account? Sign in here.
Sign In Now