Gastrontestinal Problems manifesting in the skin

[abbey]

Hi everyone and happy christmas!

 

I'm wondering how a gastrointestinal dysfunction triggers skin changes and what is the physiologic process behind it?

 

Example

• Female presents with food intolerance to histamine/amine rich food.
• Intolerance presents with acne along the jawline (trigeminal nerve dermatome region), each time histamine rich food is consumed.

 

I found a relevant article here which mentions the parasympathetic reflex phenomena as a reason and that pelvic dysfunction can be a reason for it.

http://british-institute-of-osteopathy.org/articles/the_reflex_nature_of_skin_conditions.aspx

 

But how do the neurotransmitter travel and where is the irritant for the skin condition release, and cause a symptoms at the jaw?

Is it rather a histamine response, but why is it only affecting the skin of the face and not any other region?

 

 

I just can't explain to myself why a reaction to certain food would cause such localised symptom and not manifest systemically.

All I could think of was that the histamine released in the stomach travels in the bloodstream and causes a immune response. But what in the face?

Or if it was the Hypothalamus-Pituitary-Adrenal Axis which could have involvement in this too?

 

If someone knows more about it, please let me know..

 

Thank you very much !!!!!