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CRISPR/Cas9 system for gene silencing

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Hi, I'm a newbie in biology with interest in genome engineering and I wonder if you could help me with a doubt, it may sound silly but I need to be sure.


If I introduce a lentiviral CRISPR/Cas9 system for gene silencing into a population of different types of cells, the system will only produce the silencing of genes in the cells containing the gene?


What changes could produce the lentiviral CRISPR/Cas9 system in other types of cells?

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