Jump to content

question from a beginner

Althalus
in Genetics

Featured Replies

Dear all,

 

I am currently using the Pubmed SNP database for my literature review. However, I got very confuse with information presented to me.

 

Each SNP has their own unique rs number, but how come when I keyed in an rs number, there are so many HGVS names for it? and they are all so different.

 

For example

 

rs4680 for COMT gene. there are 14 HGVS names

 

  • NC_000022.11:g.19963748G>A
  • NG_011526.1:g.27009G>A
  • NM_000754.3:c.472G>A
  • NM_001135161.1:c.472G>A
  • NM_001135162.1:c.472G>A
  • NM_007310.2:c.322G>A
  • NP_000745.1:p.Val158Met
  • NP_001128633.1:p.Val158Met
  • NP_001128634.1:p.Val158Met
  • NP_009294.1:p.Val108Met

Would be glad if someone can enlighten me. Thank you so much

Archived

This topic is now archived and is closed to further replies.

Go to topic listing

Important Information

We have placed cookies on your device to help make this website better. You can adjust your cookie settings, otherwise we'll assume you're okay to continue.

Configure browser push notifications
Chrome (Android)
  1. Tap the lock icon next to the address bar.
  2. Tap Permissions → Notifications.
  3. Adjust your preference.
Chrome (Desktop)
  1. Click the padlock icon in the address bar.
  2. Select Site settings.
  3. Find Notifications and adjust your preference.