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Tight Junctions

blazinfury
in Homework Help

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I am trying to understand the difference b/w tight junctions and desmosomes and have yet to find a major physiological one as they are both used for anchoring cells and both are impermeable. Then if they have nearly identical functions then why can't we have desmosomes in GI tract rather than tight junctions or tight junctions in skin rather than desmosomes in the epidermal layer connecting squamous epithelial cells?

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