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Immunology Homework Question (PLEASE HELP!)

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Hello everyone,


I am having some trouble with a homework question for my immunolgy
class. The question is " It has been demonstrated that mice with a
mutation in Toll-like Receptor 4 (TLR4) that differed from the normal
TLR4 by a single amino acid were resistant to septic shock caused by
fatal doses of gram-negative bacteria. Would this mutation be beneficial
or detrimental to the individual with the mutation? Explain."


To me it seems that it would be beneficial because septic shock can
kill. However, this seems too obvious and our professor never assigns
questions that seem this obvious so im hesitant about the answer. Can
anyone help me? Thanks!

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