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melatonin receptor agonist

anarchochem42
in Organic Chemistry

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I've been attempting a reaction which involves a substitution to position 2 of the indole ring for melatonin, using l-phenylalanine as the reagent. What would be required to catalyze the reaction?

  • 1 month later...

Assuming you want to carry nucleophillic acyl substitution of the carbonyl group of phenyl alanine use an acid. I think indole will attack the acyl position frrom the position 2.

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