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How much glycine and HCl to prepare this solution...

tjpj77
in Homework Help

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Calculate the amount of glycine and HCl required to prepare a 1L solution of 0.1M buffer at a pH of 2.0. The pKa of the glycine carboxyl group is 2.4 and the pKa of the amine group is 9.6. The amu of glycine is 75. Using pH = pKa + log ([A-]/[HA]), I get 2.0 = 6.0 + log ([A-]/[HA]). I get 6.0 because that is the average of the pKa values of glycine. But we can't have the log of a negative number, so I'm totally stuck here... Thanks...

Edited by tjpj77

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