Hi,

This question asks which of the following best describes the function of proteins bound at the proximal promoter elements in eukaryotic genes?

a. The bind to RNA polymerase subunits

b. They bind DNA as well as proteins

c. They play catalytic roles in transcription

d. They unwind DNA to promote polymerase binding

e. Their roles are only for activation of transcription

 

The answer is apparently B. but I thought C. was equally correct. What am I missing?

Edited November 6, 201114 yr by Lukas!

The proximal promoter is where transcription factors bind helping activation this is further away from the start codon around -250, I think you are thinking it is where the ribonuclease complex binds, the -35 region, but this is actually called the core promoter. The reason E isn't true is because they can also be repressors.

Edited November 6, 201114 yr by Psycho