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COX-3 and Acetaminophen

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I am currently doing an essay on this topic. However I have came to a problem. I can't seem to find any info on which part of acetaminophen that reacts and performs the analgesic function. Is it possible to give me few hints on this? (It has a chemical formula of C8H9NO2)

 

Also, a lot of sources indicate the lack of reaction of COX-1 and COX-2 to acetaminophen. And some suggest COX-3 is the key. Since it is first made known to public in 2002, not a lot of info can be found. Can anyone point me to the right direction for searching for its info?

  • 3 weeks later...

I'd suggest your try PubMed to search for journal articles on this subject. I only remember that COX-1 and 2 are involved in the inflammatory response and I think acetaminophen is paracetamol which is obviously a NSAID....beyond that I'm no use :confused:

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