anybody have an image of the 5HT1 receptor? i need to know the structure of it ASAP. if you find it, i would be most grateful. thank you.

does the subtype matter?

what do you mean?

Just that the 5-HT1 receptor can be further classified into subtypes, which are the 5-HT1A, 5-HT1B, and 5-HT1D (there may be a few more).

 

These are your typical 7 transmembrane spanning G-protein coupled receptors. I'm familiar with the 5-Ht1A subtype. The 5-HT1A receptor is classically coupled to an inhibition of adenylyl cycle and a decrease in cAMP. It's the serotonergic autoreceptor and is usually activated in response to high levels of 5-HT.

 

I don't think the receptor's crytal structure has been determined yet, though I could be wrong. Thus, and 7 transmembrane spanning g-protein coupled receptor will look similar to it. I'll try and attach an image.

thanks a bunch