Jump to content

Wegener's and Churg-Strauss Granulomatosis

Proteus
in Biochemistry and Molecular Biology

Featured Replies

What are the most important differences between the two?

Wegener's granulomatosis is associated with the presence of classical anti-neutrophil cytoplasmic antibodies (c-ANCA, found scattered throughout the cytoplasm), while Churg-Strauss is associated with the presence of perinuclear or protoplasmic ANCA (p-ANCA, found mainly near the nuclear membrane). The antigen in WG is typically proteinase 3, while in CS it is usually myeloperoxidase. They otherwise have extremely similar symptoms.

Archived

This topic is now archived and is closed to further replies.

Go to topic listing

Important Information

We have placed cookies on your device to help make this website better. You can adjust your cookie settings, otherwise we'll assume you're okay to continue.

Configure browser push notifications
Chrome (Android)
  1. Tap the lock icon next to the address bar.
  2. Tap Permissions → Notifications.
  3. Adjust your preference.
Chrome (Desktop)
  1. Click the padlock icon in the address bar.
  2. Select Site settings.
  3. Find Notifications and adjust your preference.