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Type III Collagen in Dermal Scars

Xittenn
in Biochemistry and Molecular Biology

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I had mentioned in a previous thread the possibility of an overabundance of Type-III Collagen as being an aiding cause in the less than complete remodeling of skin. I was 'corrected' on this subject and was told only Type-I Collagen was present in dermal tissue.

 

http://www.scienceforums.net/forum/showthread.php?t=34945&highlight=chemical+scar

 

I've come across several studies which are reviewing the role of Type-III Collagen in Dermal Scarring.

 

eg. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1163841

 

Is there anything to be said about inducing a mild and general apoptosis in a Dermal Scar with a slightly more aggressive attack on Type-III as a means of remodeling the scarred tissue????

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