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Cyclodextrin encapsulation

borodin
in Organic Chemistry

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Hi.

I'm on a little project trying to study encapsulation of 2-hydroxybenzoic and 4-hydroxybenzoic acid in alpha and beta-cyclodextrin (CD). The method is to keep constant the concentration of the acid and variate the CD concentration, adding NaCl to keep the ionic strength constant. Right now i'm only doing UV-Vis measurements and i'm having bad results (or bad data treatment). I've attachted some results. Any sugestions? I'm only using the Benesi-Hildbrand Model, the only i found to study encapsulations.

 

I'm feeling a little lost and my teacher don't have much time to dedicate to this project..

 

Thanks!!!

 

;)

 

PS - Sorry my bad english.. :S

2HB - aCD.xls.zip

Edited by borodin

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