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Hemoglobin and Binding Affinity to Oxygen

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In which one of the following situations would you expect hemoglobin to have the lowest binding affinity for oxygen?

a. in your thigh muscle after you have been running for a minute

b. just below the surface of the skin on a cold day

c. in the pulmonary vein

d. in the kidney

e. in the lung

 

I want to say A but I'm not sure. My reasoning is that the level of DPG is highest during A so the binding affinity for oxygen by hemoglobin is at its lowest.

Am I correct?

In which one of the following situations would you expect hemoglobin to have the lowest binding affinity for oxygen?

a. in your thigh muscle after you have been running for a minute

b. just below the surface of the skin on a cold day

c. in the pulmonary vein

d. in the kidney

e. in the lung

 

I want to say A but I'm not sure. My reasoning is that the level of DPG is highest during A so the binding affinity for oxygen by hemoglobin is at its lowest.

Am I correct?

 

Hmm, looks a lot like a Homework question...

 

Wikipedia has some useful information regarding the affinity of O2 to hemoglobin: I think you'll find the answer there if you consider it carefully.

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