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Enzyme kinetics - catalytic proficiency and efficiency

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Hello all...

 

I'm taking a course covering, amongst other things, simple enzyme kinetics. I'm fine with the majority, but am not quite sure of the physical significance of the catalytic proficiency and catalytic efficiency, given by

[math]proficiency = \frac{k(cat)/Km}{k(uncat)}[/math]

and

[math]efficiency = \frac{k(cat)}{Km}[/math]

respectively.

 

Can anyone shed some light on this for me?

 

Cheers

Kaeroll

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