Jump to content

Synthesis of Sulfanilamide

Featured Replies

Can someone please help me with the following question regarding the synthesis of sulfanilamide from aniline lab:

 

Comment on the feasibility of the following alternative (see image below) as a synthetic route to sulfanilamide. How could this synthesis be modified to more successfully produce sulfanilamide?

 

rxnsjpgmb2.th.jpg

rxns jpg.jpg

I would probably protect the -NH2 group with an acetyl group. Sulphonation I would probably carry out with ClSO3H (in xs) giving p-CH3C(O)NHC6H4SO2Cl. Treat with NH3 and hydrolyse to give sulphanilamide

Archived

This topic is now archived and is closed to further replies.

Important Information

We have placed cookies on your device to help make this website better. You can adjust your cookie settings, otherwise we'll assume you're okay to continue.

Configure browser push notifications

Chrome (Android)
  1. Tap the lock icon next to the address bar.
  2. Tap Permissions → Notifications.
  3. Adjust your preference.
Chrome (Desktop)
  1. Click the padlock icon in the address bar.
  2. Select Site settings.
  3. Find Notifications and adjust your preference.