what gene causes porphyria? google isn't helping, and i need to know what chromosome causes the disease. there's different kinds of porphyria, and more than one are genetic, so there may be more than one chromosome. thx in advance.

what gene causes porphyria? google isn't helping, and i need to know what chromosome causes the disease. there's different kinds of porphyria, and more than one are genetic, so there may be more than one chromosome. thx in advance.

 

There is a gene called UROD, located on Chromosome #1

that is involved with some porphyria

 

http://ghr.nlm.nih.gov/gene=urod

 

"The UROD gene provides instructions for the production of an enzyme called uroporphyrinogen decarboxylase. This enzyme is responsible for the fifth step in the production of heme, the iron-containing part of hemoglobin."

 

Mutations of the UROD gene can cause porphyria

 

"Approximately 50 mutations that cause a form of porphyria called porphyria cutanea tarda have been identified in the UROD gene..."

 

Where is the UROD gene located?

 

"Cytogenetic Location: 1p34

 

Molecular Location on chromosome 1: base pairs 45,250,416 to 45,253,927"

============================

 

A half dozen other genes are mentioned here, besides UROD:

http://ghr.nlm.nih.gov/condition=porphyria

 

This page also mentions some NON-GENETIC causes, such as HepatitisC

and alcohol-induced liver damage. It isn't always inherited

omg THANK YOU! how did you find that? did you just know what you were looking for?

generally, if you're having trouble researching a specific question, start by doing some general research about your subject. All that information that martin found can be located by a simple google search for porphyria. You may have been trying to be too specific with your search terms.

what is vampire disease?

http://en.wikipedia.org/wiki/Porphyria