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Biochemistry Exam Question

hsentar
in Biochemistry and Molecular Biology

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Question from an old exam, (studying for the final) can't figure out the answer:

 

 

"Given that pyruvate can be converted to Acetyl CoA using reactions we learned in this class, write a balanced reaction scheme for converting pyruvate to Alpha Ketoglutarate WITHOUT depleting any TCA Cycle components."

 

 

any ideas?

What type of reactions did you learn in the class?

  • Author

nothing special or out of the ordinary, i think he was just trying to drop a hint there or something... but it's not helping me solve this.

 

Pyruvate to Acetyl CoA :

 

Pyruvate + NAD >(with Pyruvate Dehydrogenase)> Acetyl CoA + NADH + CO2

 

Still... pyruvate to Alpha Ketoglutarate WITHOUT depleting TCA components... ?

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