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separate Mitochondrial culture?

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IS it possible to keep separated (out of its cell) mitochondria alive in vitro cutures?

 

(and if yes how can it be done?)

I've never heard of it, it would be tricky because most of the mitochondrial genes have migrated to the nuclear chromosomes.

Mitochondria need nuclear gene to maintain, so I think it would only be possible that at least such substances (finally translated proteins from nuclear genes) could be provided, while there is too low possibility to make to be practical. also, there may involve some communication between cells or with outside environment to maintain the mitochondria, so I think besides this is rather not practical, it would also be not possible.

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thanks for your replies..

pity. maybe it would be very good for simulation of early life forms on Earth some 3 - 4 billion years back

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