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how is IRF-1 activation happen?

konstantin
in Microbiology and Immunology

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hello everyone. I have a simple question for pundits in immunology :) .

I know that IRF-3 is activated through its phosphorylation and subsequent translocation from cytosol into nucleus.

but it is vague for me how IRF-1 is activated.

please explain or give some link where I can find useful information...

thanks in advance

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