In present days, most medicines are in tablet and capsule forms. The one i am interested in is capsule. Currently, i am doing an project on capsules, including the ingredients.

 

Is there any method to remove the colouring agent in the capsules?

almost impossible to answer that without knowing exactly what the "Ingredients" are.

but I suspect it`ll come down to the use of a solvent and perhaps centrifuge.

In present days, most medicines are in tablet and capsule forms. The one i am interested in is capsule. Currently, i am doing an project on capsules, including the ingredients.

 

Is there any method to remove the colouring agent in the capsules?

 

Aren't most capsules made from gelatin? Or some form of vegetable fiber. In that case, the natural color is tan. I think agents are added for other colors.

 

http://www.capsugel.com/

 

http://www.emptycaps.com/

 

http://www.capsuleking.com/?gclid=CPKgw76m3YcCFQimHgodPHv1lg

Tq.

 

The samples i have prepared are:

1. the whole capsule dissolved in water.

the ingredients of capsule that i found out might be

gelatin (>85%),

water (~10%),

methyl paraben, propyl paraben and Sodium Lauryl Sulphate (< 1%)

 

2. pure gelatin solution.

 

 

Now i am seaching for the HPLC-MS method to analyse my samples. Any suggestion regarding the method? such as what type of mobile phase, flow rate, buffer....