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antigen, cytotoxin and proliferation questions (+ more)

Tilda
in Biochemistry and Molecular Biology

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1) How can one stimulate proliferation and differentiation with the help of alloantigen cells? Do they work as an antigen and if so what is the co.factor?

 

2) How does it proliferate when only the co-factor IL-2 is added? Doesn't it need an antigen? or do you only need that for differentiation?

 

3) Often when they test the cytotoxin in vivo, they check it on LAK (both NK and T-cells) Why don't they only check T-cells? Is it too hard to seperate the two?

:confused:

 

Thankful for any help//

 

Tilda

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