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Looking for PDB for 7α-hydroxylase CYP7A1 in complex with cholesterol


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Hi All,

I'm looking for a PDB for 7α-hydroxylase CYP7A1 in complex with cholesterol.  I've searched in the PDB database and I've found the files for the enzyme alone, and complexed with cholest-4-en-3-one and 7-ketocholesterol, but not complexed with cholesterol.  This seems odd to me as cholesterol is its natural substrate.  Is it possible that the PDB file doesn't exist, or am I missing something?

Thanks!

John

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