Jump to content
tomallen123

What are the pKa values of the two amine groups in Carbidopa?

Recommended Posts

What are the rough pKa values of the two amine groups in carbidopa?  Do these amines form a diamine or are they seperate aliphatic amines?  I presumed they would have average pKa values for primary (9.4) and secondary amines (10.7), however drugbank says the most basic group in carbidopa has a pKa of around 5.6.  I am not sure how either of the amines have a pKa value of around this unless both of them being bonded has an effect.

Any responses would be greatly appreciated as this is help for an assignment due very soon.  Many thanks,

Tom.

Share this post


Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now

×
×
  • Create New...

Important Information

We have placed cookies on your device to help make this website better. You can adjust your cookie settings, otherwise we'll assume you're okay to continue.