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Antisense strand and ploidy

os57
in Genetics

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Hi,

 

If only one strand (the antisense strand) of dsDNA is used as a template to synthesise mRNA then why is gene dosage a thing? Two copies of the gene = one copy able to be transcribed into mRNA, one copy could mean there is one or no template available to be transcribed, depending upon whether that copy is sense or antisense?

 

thanks in advance,

O.

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