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I recieved the following response from Vicks, the company that maufactures or offers NyQuil: Thanks for your question regarding what the "Quil" stands for in NyQuil and DayQuil. As is sometimes the case with acquired brands, that specific information does not exist in our Archives. P&G acquired Richardson-Vicks (RVI), the company that introduced NyQuil, in 1985. However only a fragment of the historical files from RVI were ever turned over to P&G. In a 1999 magazine article at the time of the brand's 30th anniversary, the author conjectured that NyQuil was based on the term "nighttime tranquility." Although I can't confirm it, it would seem to be a logical guess. My apologies that I can't provide a definitive answer. I thought that this would be the response, thank you all!

I actually sent an email to Vicks the pharmaceutical company that makes it, I hope they reply with an official answer. Kyrisch, you are probably correct or on the right track. P.S. The avatar freaked me out too, that's why i used it, I hope you enjoy!

Does anyone have a history on the nomenclature for this cold/cough remedy? What does Nyquil stand for? specifically the "quil" part. If anyone has an answer please post any applicable citation as well.