Observation: Frailty includes: Muscle weakness Slower movement Fatigue Weight loss Reduced physical activity Higher risk of falls, disability, or illness It's often linked to sarcopenia (loss of muscle mass and strength), bone thinning, and neurological decline — not just hardening of bones. Solution: Acetylcholine (ACh) is a neurotransmitter important in: Muscle contraction (at neuromuscular junctions) Autonomic nervous system function Cognitive function in the brain hopefully, above solution can lengthen their lifespan to enjoy their golden years.