Moon99

I won’t live long enuf to see it, but I doubt that the US health care system is really going to make things better for the average citizen.

You make it sound like the US has the worst healthcare? It would not surprise me that Trump is making the healthcare worse in the US and cutting back on medical research. I’m surprise the rich in the US wants terrible healthcare and not phoning Trump not to cut back on the healthcare and medical research.

That is really interesting because I hear tropical countries there flu season is the summer time but in the US in the sun belt cities it is the winter time. Well cities like Los Angeles, Houston and Miami and much of Florida it is in the winter time not the summer like the tropical countries. I don’t know why that is the case?

My understanding is drugs don’t necessarily change the protein’s structure. Many drugs simply bind to the protein active site and block the native substrate from binding. So from what I understand drugs do not change the protein structure And from what I understood receptors are protein. So different receptors are different protein. The drug do not binds to the receptor molecules and changes it?

lizard lightin tail in Cambodia What is this spotted? No idea they had this in Cambodia.

Where do you see the future of medicine going in 20 years from now? In 20 years from now what will future of medicine be like? I’m wondering in 20 years from now what will medicine be like? I read some thing about gene editing?

Because it isn't exactly like a key in a keyhole, it is messier than that, and more things fit the keyhole than one exact chemical shape from what I understand . The cell isn't matching the whole chemical, but even just a side of the chemical. The keyhole being receptors and key being agonists.

So if I understand it medication changes molecule or protein in your body? And these molecule or protein do more than one thing? So they want to make drugs that change the protein or molecule but it does more the one thing the protein or molecule?

What is the conspiracy of mRNA? I thought mRNA vaccines tell your cells to make protein and these protein make large molecules and they fight the virus the virus spike that locks onto the virus spike molecules. Is this what people are afraid of? Because the mRNA vaccines tell your cells to make protein that these molecules bind to the virus spike? And that the conspiracy saying it not natural and not safe and your cells to make is making this protein?

It talks about receptors and agonists and how drugs work but it does not explain why drugs have side effects.

But what do these drugs do like how do drugs work that it has side effects.

I was having a discussion with friend and he said a lot of medication have side effects. I’m confused of why lot of medication have side effects? Is this because medication is not target therapy? Will quantum computers, AI and super computers allow for more targeted therapy?

Why do people get the cold and flu in the winter time? People say flu season is in the winter from October to April. They say it not the cold weather causing it but people indoors more but I’m confuse because in the sun belt cities like Phoenix and Miami in the summer the AC is on and they are indoors more yet they get cold and flu in the winter time there with the AC off in the winter there and not the summer. Also the window is open and they are out doors more in the winter time there. So what is causing the cold and flu to spread so much in the winter time? Other warm tropical countries where it is hot all year round get the cold and flu there.

I never heard of going on diet being part of detox. I thought detox is when you drink some thing to go to bathroom or fasting for 2 or 3 days. It says here about bananas. Bananas contain fructans — a type of FODMAP (fermentable oligosaccharides, disaccharides, monosaccharides and polyols). FODMAPS are a group of fermentable carbohydrates that can be hard to digest, sometimes worsening symptoms such as diarrhea and gas. Due to this, consider limiting bananas if they worsen diarrhea.

I don’t see any thing there on colon detox. https://www.ncbi.nlm.nih.gov/pmc/?term=colon+detox

How do I know what are some reputable sources and not sources the company is putting out to push such treatment?

What is this I hear about people doing colon detox. Is this where they drink some thing and it flushes out the colon or they are fasting for two or three days? And this colon detox what is it used for is it to help symptoms of say (IBS) Irritable bowel syndrome, crohn's Disease, colitis, bloating or gas. Also what is this I hear about colon hypnotherapy?

Could they not use stem cells and grow stem cells than transplant that in him? Or this guy needed new organ?

I can’t get data on it. But in the US 100 years ago there is data on it. That's a big change from 1900, when infectious diseases like pneumonia, tuberculosis and diarrhea accounted for almost half of all deaths. The historical decline represents great progress in sanitation, antibiotic discovery and vaccination programs, says Heidi Brown, an assistant professor of public health at the University of Arizona and an author of the research letter. "We've done phenomenal and amazing things with respect to infectious diseases," she says. NPRInfectious Diseases Keep Delivering Surprises To The U.S.The death toll from pneumonia and other infectious diseases in the U.S. is much lower than it was 100 years ago, but new pathogens like the West Nile, dengue and Zika viruses pose challenges. Vaccination Strategic vaccination campaigns have virtually eliminated diseases that previously were common in the United States, including diphtheria, tetanus, poliomyelitis, smallpox, measles, mumps, rubella, and Haemophilus influenzaetype b meningitis (8). With the licensure of the combined diphtheria and tetanus toxoids and pertussis vaccine in 1949, state and local health departments instituted vaccination programs, aimed primarily at poor children. In 1955, the introduction of the Salk poliovirus vaccine led to federal funding of state and local childhood vaccination programs. In 1962, a federally coordinated vaccination program was established through the passage of the Vaccination Assistance Act--landmark legislation that has been renewed continuously and now supports the purchase and administration of a full range of childhood vaccines. The success of vaccination programs in the United States and Europe inspired the 20th-century concept of "disease eradication"--the idea that a selected disease could be eradicated from all human populations through global cooperation. In 1977, after a decade-long campaign involving 33 nations, smallpox was eradicated worldwide--approximately a decade after it had been eliminated from the United States and the rest of the Western Hemisphere. Polio and dracunculiasis may be eradicated by 2000. Antibiotics and Other Antimicrobial Medicines Penicillin was developed into a widely available medical product that provided quick and complete treatment of previously incurable bacterial illnesses, with a wider range of targets and fewer side effects than sulfa drugs. Discovered fortuitously in 1928, penicillin was not developed for medical use until the 1940s, when it was produced in substantial quantities and used by the U.S. military to treat sick and wounded soldiers. Antibiotics have been in civilian use for 57 years (see box 1) and have saved the lives of persons with streptococcal and staphylococcal infections, gonorrhea, syphilis, and other infections. Drugs also have been developed to treat viral diseases (e.g., herpes and HIV infection); fungal diseases (e.g., candidiasis and histoplasmosis); and parasitic diseases (e.g., malaria). The microbiologist Selman Waksman led much of the early research in discovering antibiotics (see box 2). However, the emergence of drug resistance in many organisms is reversing some of the therapeutic miracles of the last 50 years and underscores the importance of disease prevention. https://www.cdc.gov/mmwr/preview/mmwrhtml/mm4829a1.htm

Is this CRISPR-Cas9 or some other CRISPR? First gene-edited islet transplant in a human passes functional trial. Uppsala University Hospital-led investigators report that gene-edited donor islet cells survived 12 weeks inside a man with long-standing type 1 diabetes without any immunosuppressive medication. https://medicalxpress.com/news/2025-08-gene-islet-transplant-human-functional.html And why did they deigned it to only last 12 weeks? After 12 weeks would problem not come back? Why did they not use gene editing on his own cells?

What infections are you talking about back in that time? These infections 5 ancient diseases and what the ancients said about them https://www.gavi.org/vaccineswork/5-ancient-diseases-and-what-ancients-said-about-them Or these 14 Diseases Nearly Eliminated by Vaccines https://resources.healthgrades.com/right-care/vaccines/14-diseases-nearly-eliminated-by-vaccines

What where the virus and bacteria back than killing so many people and babies?

It is not just the Middle Ages. In ancient Egypt they did not live long. https://blogs.ucl.ac.uk/researchers-in-museums/2015/03/02/old-age-in-ancient-egypt/ People in ancient Egypt did not grow very old. Very high infant death rates due to high risks of infections resulted in an average age at death of 19 years. However those who survived childhood had a life expectancy of 30 years for women* and 34 years for men. Most ancient Egyptians were unlikely to live beyond 40 years of age

From my understanding there talking about using CRISPR-Cas9 to treat including rheumatoid arthritis (RA), inflammatory bowel diseases (IBD), systemic lupus erythematosus (SLE), multiple sclerosis (MS), type 1 diabetes mellitus (DM), psoriasis, and type 1 coeliac disease. QUOTE Autoimmune diseases are disorders that destruct or disrupt the body's own tissues by its own immune system. Several studies have revealed that polymorphisms of multiple genes are involved in autoimmune diseases. Meanwhile, gene therapy has become a promising approach in autoimmune diseases, and clustered regularly interspaced palindromic repeats and CRISPR-associated protein 9 (CRISPR-Cas9) has become one of the most prominent methods. It has been shown that CRISPR-Cas9 can be applied to knock out proprotein convertase subtilisin/kexin type 9 (PCSK9) or block PCSK9, resulting in lowering low-density lipoprotein cholesterol. In other studies, it can be used to treat rare diseases such as ornithine transcarbamylase (OTC) deficiency and hereditary tyrosinemia. However, few studies on the treatment of autoimmune disease using CRISPR-Cas9 have been reported so far. In this review, we highlight the current and potential use of CRISPR-Cas9 in the management of autoimmune diseases. We summarize the potential target genes for immunomodulation using CRISPR-Cas9 in autoimmune diseases including rheumatoid arthritis (RA), inflammatory bowel diseases (IBD), systemic lupus erythematosus (SLE), multiple sclerosis (MS), type 1 diabetes mellitus (DM), psoriasis, and type 1 coeliac disease. This article will give a new perspective on understanding the use of CRISPR-Cas9 in autoimmune diseases not only through animal models but also in human models. Emerging approaches to investigate the potential target genes for CRISPR-Cas9 treatment may be promising for the tailored immunomodulation of some autoimmune diseases in the near future. QUOTE What is this CRISPR-Cas9 how would they treat it? Are they changing the genes or turning the genes off? PubMedGenome Editing Using CRISPR-Cas9 and Autoimmune Diseases:...Autoimmune diseases are disorders that destruct or disrupt the body's own tissues by its own immune system. Several studies have revealed that polymorphisms of multiple genes are involved in autoim...

Why infants and children died at a horrific rate in the Middle Ages? Quote For starters, infants and children died at a horrific rate (some say up to 1/3 of all died before the age of 5) Quote https://www.sarahwoodbury.com/life-expectancy-in-the-middle-ages/ Why did infants and children died at a horrific rate in the Middle Ages? Most people only lived to mid 40s. What happen in the Middle Ages people died so early? Was there just more bacterial and virus back in that time?