phil-d

thanks - i might try some polysorbate or something and see if that helps

yes no problem...im basically attempting to replicate an experiment i have read about online where someone has used a 10% sodium bicarbonate solution mixed with DMSO. For my own reasons i am attempting to diverge and used ethanol / glycol as the penetrating vehicle (DMSO suffers the same solvent issues by the way). I am struggling to figure out how they managed to add DMSO without the bicarbonate precipitating out?

Hi, I am afraid i am a bit of a chemistry dimwit, but i will ask anyway: I am attempting to dissolve a water soluble compound into an ethanol / propylene glycol solution. The problem is the compound is insoluble in ethanol / glycol, but fully soluble in water. My first attempt was to create a solution in water (successful) then add the ethanol / glycol afterwards....problem is the compound then seems to precipitate out (seems to collect at the bottom of the flask). Is there a way to do this? i thought maybe heat the solution to try and break the bonds? Is there an additive i can add (bearing in mind this is for applying to skin). Sorry if this is a stupid question. Thanks for you help