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alomna

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  1. alomna

    Can I conclude the mode of action of an antimicrobial compounds in the results?

    alomna posted a topic in Microbiology and Immunology
    I am writing my thesis/dissertation. It dealt with the antimicrobial activity of novel compounds. Next to determining the MIC, I also subcultured the organisms to conclude about the mode of action. I determined the MBCs for every compound and also calculated the MBC/MIC ratio. This ratio tells me more about the potential mode of action (static or cidal). For instance, smaller than 4 would be bactericidal. I don't know how to deal with these results. Can I already assign the mode of action after naming the results, or should this be part of the discussion? I had the same question about my synergy experiment. I tested two compounds together and calculated the fractional inhibitory index. I concluded that no interaction was observed in my results. Is this correct?

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