B_Stem
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Hello,
i was reading an article about temporal control of cortical mammalian neurogenesis and the authors say that RGCs (radial Glial Cells) act as neural stem cells and differentiate into IPC (Intermediate Progenitor Cell). Then, these IPCs can differentiate into neurons. (RGC => IPC => Neurons)
But later in the paper, they talk about NPC (neural progenitor cell) and i'm a bit confused by this term. So here is my question :
- is NPC a group of different kind of progenitors in which are IPCs ? And if yes, why do they talk about NPC and not IPC ?
Thank you
Paper : Temporal Control of Mammalian Cortical Neurogenesis by m6A Methylation (Cell, 2017)
0
Neural Progenitor Cells (NPC) and Intermediate Progenitor Cell (IPC)
in Biochemistry and Molecular Biology
Posted
Thank you very much for your answer. I'm glad i'm not the only one confused by this mess...
As I understand, NPCs include RGCs and BPs (=IPC). But I don't understand why the authors are suddenly talking about NPCs. The first time they talk about NPCs is in the results : "
we performed time-lapse imaging of individual cortical neural progenitor cells (NPCs) cultured from E13.5 mouse cortex".
So does that mean that they don't make the difference between RGCs and IPCs ?