TheCHEMISTRYstudent
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Aniline as Nucleophile vs Electrophilic Aromatic Substitution
in Organic Chemistry
Posted
In the reaction Aniline + Ethyl acetoacetate ----> bicylic product, is Aniline more likely to react as a nucleophile first at the amine end; by attacking the ketone in ethyl acetoacetate, or is it more likely to be involved in an electrophilic aromatic substitution at the activated ortho position.
Textbooks are so bad at these kinds of questions. i.e which is the most reactive part of this given molecule?
Thanks for any replies.