mahi_007

Hello As you know SP cells possess CSC-like phenotypes, just wonder why verapamil (which known a drug-resistance cancer) can blocks SP cells? Whats the reason that this drug can diagnosis SP cells from MP cells(main population)?

Hi, Can someone tell me What is the main difference between cancer stem cells and cancer cells? Thanks

Hello i have a question about the expression of miRNAa in cancer tissues I want to know does it always mean promoting invasion and metastasis when a miRNA upregulates in cancers?

Hello, Im reading a book called:Textbook of Personalized Medicine As part of the book defines SNP but its written a few obstacles for their use which I do not understand well. Do you know why these 4 items are considered as the obstacles for the use of it? I put the part of the book related to SNP: "Using SNPs or a small set of SNPs is considered to be an excellent tool to discover genes for psychiatric disorders and potentially an excellent tool for psychopharmacogenetics as well. There are, however, a few obstacles for their use: (1) high-throughput, low-cost genotyping assay systems; (2) definitions of good disease phenotype; (3) a good collaboration effort among geneticists, epidemiologists, and physicians; (4) a good candidate gene(s)".

Hi, Im researching to find a list of miRNAs in melanoma CSCs but unfortunately I havent been able to find an article which exclusively related to melanoma stem cell . Do you know any paper about this topic?

Hello can anyone help me the meaning of Profiling miRNA in this topic? miRNA Expression Profiling in Melanocytes and Melanoma Cell Lines Reveals miRNAs Associated with Formation and Progression of Malignant Melanoma