Plutocracy

Thank you a ton for your response! The histogram shows that methylation was discovered around the same time as acetylation, but the papers on DNA methylation were published at a much faster rate. I didn't know that bisulfite sequencing and ChIP were used as assays; I just assumed the ones were gel electrophoresis and RNA extraction.

Hi all, I'm wondering why there are more scientific papers published on methylation over acetylation. On PubMed, there are 50k results when I type in "DNA methylation", but only 12k results when I type in "histone acetylation". Is there any clear reason why? Methylation being easier to assay, having more clinical importance, or being discovered earlier? Please let me know .