schafer Posted January 28, 2016 Share Posted January 28, 2016 Hello, From reading about smooth muscle relaxation, I understood that MLCP enzyme (myosin light chain phosphatase) dephosphorylates the myosin. This leads to relaxation because dephosphorylated myosin is unable to bind actin in smooth muscle cells. However, some smooth muscle cells have 'latch state' where myosin heads remain attached to the actin even after dephosphorylation. I don't really understand what causes the difference between the two cases. In one, dephos. causes relaxation while in the other it causes prolong binding. Anyone knows the explanation? Link to comment Share on other sites More sharing options...
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