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Citric Acid Cycle Help


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Hello, I am new to this forum, so I am sorry if this sort of posting already exists or if it is posted in the wrong category. I am currently struggling with my Biochemistry homework to get my bachelors in Nursing. I need to locate where in the citric acid cycle a hypothetical defect of an enzyme could occur that would decrease the overall ATP production, including the consequences of the defect. Im also looking to explain the effect of the defect in one of the 8 citric acid enzymes (ie. Citrate, Cis-Aconitate, D-Isocitrate, etc) on ATP generation. If somebody could attempt to help me, explain the kreb's cycle to me, or even appoint me to a place that could efficiently explain it to me, much would be appreciated. Thanks!

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