./Jack

Hello everybody, I'm doing my biochemistry exam review and I stumbled upon a few questions, I can't find anything about on google. The question is: Now, the correct answer was B, because the given sequence contained a lot of the MALEK amino acids, which are preferred in an alpha helix structure. However, because of answer A and B, I was wondering if there is a way to tell if a sequence will be a parallel or anti-parallel beta sheet based on the contained amino acids. I know that beta sheets contain a lot of FIVTYW amino acids, but I can't find anywhere if there's a difference in parallel vs. anti-parallel. Thank you for your time Jack

Hello everybody, I'm doing my biochemistry exam review and stumbled upon a question from last years exam, I really can't get anything out of google. The question goes as follows: Correct is answer C. However, I can't quite figure out why. My reasoning so far: -> If the Beta strands were connected by (short) alpha helices, the protein wouldn't be 90% Beta sheets, so B is out. -> I've never heard of domains packing against each other, and since they fold independently, I don't think this is right. But this is both rather washy reasoning. I can't figure out what information the "two 10 kDa domains" is supposed to give me. Thank you for your time and any tips Jack