Why perception is dulled over time?

[Moreno]

Some people who fell in love with each other and married could lose interest to each other after some period of time. When you listen some melody and like it very much, you may find that it doesn't cause the same feelings in you after you hear it 100 times. You may lose interest to some type of delicious food if you eat it too often. Many drug addicted people switch to larger doses or stronger drugs with time. Etc.

 

What is a neurological mechanism of it? What happens to brain?

[Lyudmilascience]

these are all different reactions, drug addiction is different then falling out of love.

http://www.nytimes.com/1987/03/17/science/intensity-of-emotion-tied-to-perception-and-thinking.html?pagewanted=all

there are some studies show that highly emotional people will be highly emotional throughout life. this dosent relate as much to your topic but it might be informative.

some people get strong emotions , people who get strong emotions other people don't see it as those do these people have more complex lives.in one study people kept a journal of emotions from their day to day lives and were graphic shown images the emotional people reacted on emotion but the unemotional were focused on general findings, what color pants they were wearing and did not react that much to the entire situation. study suggests that your level of emotion is inherited in genetics. so people who are more emotional probably don't loose love for each other over a period of time as much as people who are not emotional. this article talked more about being strongly emotional but I can relate it to loos of love over time because those people have a different perception of love then unemotional people. its just hard to generalize every one.

 

http://www.slate.com/blogs/quora/2013/03/25/why_does_love_lose_its_intensity_with_time.html

these are responses from different people about love intensity. new relationships feel like being in new hotel, its exiting and not much work goes into it but after a while its more like owning a house you still like it but you have to put work to it. there were brain scans done of people go into relationships for a few weeks and few years thoes scans showed that after a while people had different parts of the brain activated thoes relative to long term attachments and the conclusion is that you cant compare a new relationship to an old one because they are very different. relationships fail because there is no more infatuation and they really didn't love them.

I couldnt find anything regarding to loos of interest in music.

I can go into drugs and loss of interest of taste drugs and food have very similar neurology behind them but i dont want to spend too much time writing this all out, im a slow typer and I spent too much time looking for articles so i will just linc the articles and copy and paste things that answer your question.

http://alcoholrehab.com/addiction-articles/addiction-dependence-and-tolerance/

"Physical dependence refers to how the body experiences physiological adaptation in response to chronic use of a drug. Humans adapt so well to having these substances in their system that they suffer negative consequences if the drug is stopped abruptly – these are referred to as withdrawal symptoms. These withdrawal symptoms do not only occur with recreational drugs – they can also occur with other medications such as antidepressants. Those who develop a physical dependence will often usually develop tolerance to the drug as well. It differs from addiction because it is a physiological state and not a dysfunctional behavioral syndrome. It would be correct to say that most addicts will have developed a physical dependence on their drug."

"Dopamine in the brain creates the experience of pleasure and well being. The neurotransmitter serotonin reduces pain–the highs of anxiety and the lows of depression. The biochemistry of how food, especially refined foods, can lower the blood sugar and trigger serotonin release has long been known. This biochemical mechanism was first pointed to by Wurtman et al in 1988 as the possible mechanism of food addiction. It works like this: Insulin released in the digestion of simple carbohydrates lowers the blood sugar level, and tryptophan, another amino acid, goes more easily to the brain and creates a serotonin reaction."http://foodaddictioninstitute.org/scientific-research/physical-craving-and-food-addiction-a-scientific-review/