Biology

[lisapoor]

How many net ATP's do you get from 1 glucose after glycolysis? after aerobic respiration?

[chuinhen]

after glycolysis the net ATP u obtained is 2 molecules

 

after the whole aerobic respiration :

 

Glycolysis : 2 ATP 2 NADH

Link reaction : 0 ATP 2 NADH

Krebs cycle : 2 GTP 6 NADH 2FADH2

 

 

1 NADH contributes 3 ATP energy in the Electron transport chain

1 FADH2 contribute 2 ATP energy in the electron transport chain

 

thus ,

total ATP molecule 4 + (10 X 3) + (2 X 2) = 38 ATP molecules

[[Tycho?]]

Am I experiencing a forum error here? Isn't this the physics forum? It says physics at the top of the page anyway.

[Cap'n Refsmmat]

Right, moved.

[Skye]

Experimentally the number is a bit lower, something like 35 molecules as a maximum.

[Yggdrasil]

One issues to consider is the fact that the electron transport chain (which extracts energy from the conversion of NADH to NAD⁺) occurs in the mitochondria while the two NADH produced by glyceraldehyde-3-phosphate in glycolysis are in the cytoplasm. One means of transporting the energy in the cytosolic NADH to the mitochondria (the glycerophosphate shuttle) transfers the energy from NADH to FADH₂ so the two cytosolic NADH produce a net of only four ATP. However, the Malate-Aspartate Shuttle can shuttle the energy from NADH into the mitochondria without significant loss of energy, giving six ATP from the two cytosolic ATP. Since both processes occur simultaneously, the two cytosolic NADH give a net of somewhere between 4-6 ATP.

 

Furthermore, as Syke noted, the ATP produced per NADH and FADH₂ may be closer to 2.5 to 1.5, respectively, although most texts cite the numbers given by chuinhen.