beachbum Posted February 22, 2006 Share Posted February 22, 2006 Does anyone know of a nonspecific (if that exists) caspase inhibitor or inhibitors of caspase-3 and/or caspase-8? in addition, what assay technique would you need to measure the activation/activity of a caspase? Link to comment Share on other sites More sharing options...
PapainLCP Posted December 9, 2017 Share Posted December 9, 2017 Ok, I think that this is quite old so you might know by now. You can use an specific substrate with a warhead that binds covalently. There are several assays from luminescent/ fluorescent assays both in vivo and in vitro or commonly used fluotimetric peptides with tags that can be afterwards detected. Link to comment Share on other sites More sharing options...
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