CrystalMagic Posted January 29, 2023 Share Posted January 29, 2023 Gradually, the bacteria adapt to antibiotics. In the nature of bacteria, viruses sometimes win. In the future, when antibiotics stop working on bacteria, we should be ready to use viruses. Do you think this is possible? Link to comment Share on other sites More sharing options...
joigus Posted January 29, 2023 Share Posted January 29, 2023 Viruses that target bacteria are known as bacteriophages. Bacteriophages have been tried as possible medicine. The idea is at least a century old or more. It is my understanding that the level of success was very limited. Experts can give you a more complete account. Google for "bacteriophages as antibiotics" and you will find many entries. 1 Link to comment Share on other sites More sharing options...
CrystalMagic Posted January 29, 2023 Author Share Posted January 29, 2023 1 hour ago, joigus said: Viruses that target bacteria are known as bacteriophages. Bacteriophages have been tried as possible medicine. The idea is at least a century old or more. It is my understanding that the level of success was very limited. Experts can give you a more complete account. Google for "bacteriophages as antibiotics" and you will find many entries. Yes, thank you. I've read about it. I know it's not working right now. I wonder if in the future it will become something that will save humanity if antibiotics stop working? Link to comment Share on other sites More sharing options...
joigus Posted January 29, 2023 Share Posted January 29, 2023 Right off the top of my head, using bacteriophages by means of suitable biotechnology is by no means a crazy idea. After all they're --what-- a couple thousand bases in their nucleic acid sequence? I'm guessing the reason why it hasn't been proven efficient might be related to the human body's immune response to pieces of alien DNA/RNA set loose in the body fluids. But I don't know. Maybe @CharonY --who is the resident expert in bio-- might find some time to answer the questions I'm just able to guess at right now. I do remember reading that people were considering this option again. Link to comment Share on other sites More sharing options...
CrystalMagic Posted January 29, 2023 Author Share Posted January 29, 2023 8 minutes ago, joigus said: Right off the top of my head, using bacteriophages by means of suitable biotechnology is by no means a crazy idea. After all they're --what-- a couple thousand bases in their nucleic acid sequence? I'm guessing the reason why it hasn't been proven efficient might be related to the human body's immune response to pieces of alien DNA/RNA set loose in the body fluids. But I don't know. Maybe @CharonY --who is the resident expert in bio-- might find some time to answer the questions I'm just able to guess at right now. I do remember reading that people were considering this option again. I don't have exact information, but I have heard that this area is being studied in Georgia. I would also like you to answer the question about the possible uselessness of all antibiotics in the future is this possible? Link to comment Share on other sites More sharing options...
CharonY Posted January 29, 2023 Share Posted January 29, 2023 It won't be a magic bullet. Phages have their place, but they are not ax universal as antibiotics used to be and have range of other limitations. While we need more options in the future, so far no solution presented itself. So far mitigating antibiotics use might be more important. It is bit like climate change. There are clear mid-term strategies, but we won't commit to them, so we keep hoping that somehow new technologies will save us. Link to comment Share on other sites More sharing options...
PhilGeis Posted February 1, 2023 Share Posted February 1, 2023 antibiotics-09-00135-v2.pdf Link to comment Share on other sites More sharing options...
Phi for All Posted February 1, 2023 Share Posted February 1, 2023 20 minutes ago, PhilGeis said: antibiotics-09-00135-v2.pdf 290.57 kB · 2 downloads ! Moderator Note Can you give us a quote or even a comment about how you want this document handled as part of the discussion, please? You aren't supposed to simply post links or videos or anything that has to be opened without giving the membership a reason why. Link to comment Share on other sites More sharing options...
PhilGeis Posted February 1, 2023 Share Posted February 1, 2023 3 hours ago, PhilGeis said: antibiotics-09-00135-v2.pdf 290.57 kB · 2 downloads Review - notes value in combined therapy - bacteriophage and antibiotic. Suggest folks remember their virology lab with bacteriophages and E. coli from sewage - the ease with which resistance was demonstrated 2 Link to comment Share on other sites More sharing options...
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